Combined modality therapy in the adjuvant treatment of uterine serous carcinoma

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Combined modality therapy in the adjuvant treatment of uterine serous carcinoma

Uterine serous carcinoma (USC) represents a clinically aggressive and highly malignant endometrial cancer. Initially distinguished from other types of primary endometrial adenocarcinoma in 1982, Hendrickson et al. [1] performed a pathologic review of 256 stage I endometrial cancers treated at Stanford University, with 26 of the cases revealing USC. Of these cases, 40% had deep myometrial invasi...

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Within the framework of two phase III clinical trials, the superior results of concomitant chemotherapy and radiotherapy in the treatment of patients with locally advanced anal carcinoma were demonstrated. A further phase III clinical trial showed that the role of mitomycin C as part of the concomitant chemotherapy in combination with 5-fluorouracil appeared to be essential in obtaining a highe...

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Adjuvant postoperative combined-modality therapy for rectal cancer.

A number of advances have been made in the use of adjuvant chemotherapy for resectable rectal cancer. Whereas pelvic radiation therapy has been shown to increase local control in patients with clinically resectable disease, systemic chemotherapy is needed in addition to further improve local control and overall survival. In this review, the experience treating patients with clinically resectabl...

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Adrenal Metastasis from Uterine Papillary Serous Carcinoma

BACKGROUND Uterine papillary serous carcinoma (UPSC) is a highly malignant form of endometrial cancer with a high propensity for metastases and recurrences even when there is minimal or no myometrial invasion. It usually metastasizes to the pelvis, retroperitoneal lymph nodes, upper abdomen, and peritoneum. However, adrenal metastases from UPSC is extremely rare. Here, we present a case of UPS...

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ژورنال

عنوان ژورنال: Journal of Gynecologic Oncology

سال: 2016

ISSN: 2005-0380,2005-0399

DOI: 10.3802/jgo.2016.27.e13